Researchers discover cure for common cold with a drug molecule
16 May, 2018, 00:46 | Author: Earnest Bishop
Last year, a group of European scientists announced they had found a way to decode encrypted signals in the genome of human Parechovirus, which is part of the family of viruses that causethe common cold.
One of the most common classes, however, is rhinoviruses.
But researchers in the United Kingdom have identified the protein in human cells - N-myristoyltransferase (NMT) - that the virus needs to copy itself. A newly tested molecule appears to offer real hope. The molecule could also work against the poliovirus and the virus that causes foot and mouth disease.
ISTOCK, DR_MICROBEResearchers have developed a compound that blocks the replication of rhinoviruses, the pathogens behind most cases of the common cold.
The new treatment worked within minutes on human lung cells and research leader Professor Ed Tate said he was "optimistic" his team have finally found a cure. The researchers have made a molecule that has shown to the ability to block the multiple strains of the most common cold virus, rhinovirus. The viruses also tend to evolve and build up resistance against drugs rapidly. The results were recently published in Nature Chemistry.
Solari said that is important, since the virus uses the enzyme to assemble the protein coat which surrounds the genetic material of the virus. Instead it suppresses a human enzyme that the virus relies on to construct its capsid shell. The researchers showed that the new molecule completely blocked several strains of the virus without affecting human cells. However, further studies are needed to ensure that the drug is not toxic in the body.
This approach is also advantageous as the virus can not develop resistance when the drug only affects the human protein, added the researchers.
Any virus needs this same human protein to make new copies of itself and, as this new molecule can target NMT, it can work against the common cold.
Previous attempts to create drugs that target human cells rather than the virus have proven to be failures, while also showing themselves to be toxic.
Jada and Adrienne are immediately shocked, revealing that they had no idea the young singer was going through that. It was just so insane and I was plunged into this black hole, and I was cutting myself", she continued.
Deepika Padukone is representing cosmetics brand L'Oreal at Cannes Film Festival and tonight was her final appearance for 2018. But it seems as if she is no in a mood to get it removed since she believes that it is a part of her life.
The brawl makes its way back into the arena and Reigns hit a superman punch on Jinder before officials break it up. Reigns demands he is added into the match but Angle confirms he will not be offered any more opportunities.
The network has handed out an abbreviated 13-episode sixth season renewal to Marvel's Clark Gregg drama to Agents of SHIELD . Today during a press call, ABC President Channing Dungey confirmed that Season 6 will air its 13-episode run in Summer 2019.
I was tight in traffic there then Blaney was side-drafting really hard and I was as high as I could get and we made contact. The Roush Fenway Racing driver then had an uneventful conclusion to his first race of the 2018 season, finishing 36th.
Christie said his state's "long experience" of casino gaming shows that New Jersey can appropriately regulate sports gaming. Monmouth Park Racetrack in the northern part of the state has been particularly eager to begin sports betting.
The chance for hail, strong winds, and tornadoes is highest in northeast Pennsylvania, the Hudson Valley, and western New England. All Metro North service in and out of Grand Central has been temporarily suspended until the severe weather passes.
The network renewed eight dramas , including " Lethal Weapon ", which is being revamped with a new co-star in Seann William Scott. The show seemed to do the best on Sunday nights, but Fox wanted to give Bob's Burgers a chance to "grow" in that slot.
Zidane no ha pedido a Neymar
Ahora hay dos partidos para prepararla y lo vamos a hacer bien", resaltó el estratega francés. El Real Madrid puede ganar ante el equipo inglés su tercera Liga de Campeones consecutiva .
Marvel Studios Confirms Ms. Marvel (Kamala Khan) for the MCU
She can stretch her limbs to great lengths and widths, as well, grow herself up or shrink herself down... and, back again. Marvel bosses have confirmed Ms Marvel will be joining the MCU, and fans are divided over who should play the character.
Facebook Suspends 200 Apps To Investigate Data Misuse
The app had been operating for four years when, in April of this year, Facebook suspended it, the social network confirmed. He said Facebook would notify users about such bans and make it possible for them to check whether their data was misused.