Researchers discover cure for common cold with a drug molecule

16 May, 2018, 00:46 | Author: Earnest Bishop
  • Common cold

Last year, a group of European scientists announced they had found a way to decode encrypted signals in the genome of human Parechovirus, which is part of the family of viruses that cause the common cold.

One of the most common classes, however, is rhinoviruses.

But researchers in the United Kingdom have identified the protein in human cells - N-myristoyltransferase (NMT) - that the virus needs to copy itself. A newly tested molecule appears to offer real hope. The molecule could also work against the poliovirus and the virus that causes foot and mouth disease.

ISTOCK, DR_MICROBEResearchers have developed a compound that blocks the replication of rhinoviruses, the pathogens behind most cases of the common cold.

The new treatment worked within minutes on human lung cells and research leader Professor Ed Tate said he was "optimistic" his team have finally found a cure. The researchers have made a molecule that has shown to the ability to block the multiple strains of the most common cold virus, rhinovirus. The viruses also tend to evolve and build up resistance against drugs rapidly. The results were recently published in Nature Chemistry.

More news: Laxative-laced brownies baked for coworker send-off
More news: Primer teaser tráiler de Bohemian Rhapsody, la película de Queen
More news: ¿Usas Banorte o BanBajío? Hackers robaron ¡400 mdp de bancos!

Solari said that is important, since the virus uses the enzyme to assemble the protein coat which surrounds the genetic material of the virus. Instead it suppresses a human enzyme that the virus relies on to construct its capsid shell. The researchers showed that the new molecule completely blocked several strains of the virus without affecting human cells. However, further studies are needed to ensure that the drug is not toxic in the body.

This approach is also advantageous as the virus can not develop resistance when the drug only affects the human protein, added the researchers.

Any virus needs this same human protein to make new copies of itself and, as this new molecule can target NMT, it can work against the common cold.

Previous attempts to create drugs that target human cells rather than the virus have proven to be failures, while also showing themselves to be toxic.

Recomendado:



Popular

Corea del Norte amenaza con cancelar cumbre Kim-Trump
El mes pasado, durante una cumbre intercoreana, los dirigentes de las dos Coreas se comprometieron con el objetivo de desnuclearización de la península.

Severe Thunderstorm Watch is in effect for Tompkins County
The chance for hail, strong winds, and tornadoes is highest in northeast Pennsylvania, the Hudson Valley, and western New England. All Metro North service in and out of Grand Central has been temporarily suspended until the severe weather passes.

A Star Wars Story Showcases New Droids, Creatures, and Locations
Rumors of a sequel first started circling media outlets after Ron Howard responded to some fans on Twitter in June of a year ago . In fact, he was in the trailer - but you nearly certainly didn't recognise him, because he was playing a Wookiee.

NASA Sending Tiny Helicopter to Fly over Mars in 2021
NASA's Launch Services Program, based at the agency's Kennedy Space Center in Florida, is responsible for launch management. Thus far, all our explorations of Mars have taken place from space or on the surface with rovers .

Streaky Harvick Wins Kansas Cup Series Race
I was tight in traffic there then Blaney was side-drafting really hard and I was as high as I could get and we made contact. The Roush Fenway Racing driver then had an uneventful conclusion to his first race of the 2018 season, finishing 36th.

Marvel Studios Confirms Ms. Marvel (Kamala Khan) for the MCU
She can stretch her limbs to great lengths and widths, as well, grow herself up or shrink herself down... and, back again. Marvel bosses have confirmed Ms Marvel will be joining the MCU, and fans are divided over who should play the character.

Elige Parlamento catalán a separatista como nuevo Presidente de la Generalitat
Nueve de los dirigentes secesionistas se encuentran en prisión provisional, y siete, entre ellos Puigdemont, en exilio voluntario .

Pensaron que criaban un perro y era un oso en extinción
En el chequeo que le realizaron, se comprobó que no tenía ningún problema en su salud. En China una familia adoptó a un cachorro de lo que creían era un mastín tibetano .

Jets Look To Extend Series Lead Over Golden Knights
Winnipeg emerged victorious in Game 1, winning 4-2 behind goals from four different players and three assists from Blake Wheeler. This is probably an unexpected development for the Capitals. "The bigger the game, the better he plays".

US Embassy Opens In Jerusalem; Early Voting Begins For Runoff Elections
I'm going to be thanking God for the strong leadership of Benjamin Netanyahu, who is absolutely determined to protect Israel. Jeffress delivered a sermon at a private church service just prior to Trump's inauguration in January 2017.